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Please answer multiple choice questions 1-15 Wednesday May 3, 2017 An excess of

ID: 78669 • Letter: P

Question

Please answer multiple choice questions 1-15 Wednesday May 3, 2017 An excess of is most likely linked to: fingers apoptosis separation between A Developmental problem such as lack of B. D. Excessive number of cells in tissues E. None of the above 12) which statement about cell death and inflammation is TRUE? A. Only the intrinsic pathway of apoptosis causes inflammation. B. Only the extrinsic pathway of apoptosis causes inflammation. regardless of which pathway is C. Only apoptosis that occurs during causes inflammation, development activated D. Only necrosis causes inflammation. a virus is the major cause cervical cancer. The virus awants" the infected cell to undergo continuous uncontrolled cell division. Which mechanism would not help the virus attain its goal? A. Aviral protein prevents the tumor suppressor p53 o trigger apoptosis of infected cells. B. A viral protein activates the Ras oncogene. c A viral protein prevents the tumor suppressor Rb to slow down the cell cycle at the G1/s checkpoint. D. A viral protein prevents DNA replication. E. All of the above. 14) Which checkpoint is used by the cell to control that DNA is properly segregated between daughter cells? A. G2/M checkpoint. B. G1/s checkpoint. C. Mitosis promoting checkpoint D. Spindle Assembly checkpoint. E. This does not need any specific checkpoint since the cell always makes sure the DNA is properly replicated. 15) which statement about the protein Rb (retinoblastoma protein) is FALSE? A. Rb is regulated by phosphorylation by a cyclin-dependent kinase. B. A gain of function mutation of Rb increases the risk of the cell to become cancerous. Rb blocks the transcription of genes which products are involved in the S phase of the cell cycle. D. Rb is a tumor suppressor.

Explanation / Answer

11. E. None of the above is the right answer. Process of programmed cell death or apoptosis is required for the normal development to occur. Cancer, autoimmune diseases and viral infections are the ones which are associated with deficient apoptosis and heart diseases, stroke neurodegenerative diseases etc., are associated with excessive apoptosis.