I would like to know if there are specifics when determining potential energies
ID: 789830 • Letter: I
Question
I would like to know if there are specifics when determining potential energies for staggered conformations when there are for example 2 substituents in the front carbon and 2 substituents in the back carbon.
Is there a specific rule as far to calculate energies?
I know gauche interactions are 3.8 kj/mol but is this only for the gauche interaction of Methyls? what happens when you have for example two OH groups in a gauche interaction or an OH and Me in a gauche interaction?
Do you simply just decide off of how many gauche interactions are in the molecule without calculating energies to decide which is more/less stable?
Explanation / Answer
yeah we can decide without seeing their energies...
generally gauche interactions are more stable so we will try to make the stable conformations ....
generally if two OH's are present then the more stable form is when they come closer and forms hydrogen bonding ....
ask me if you have any doubts