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The common catabolic pathway consists of: a. the citric acid cycle b. oxidative

ID: 79993 • Letter: T

Question

The common catabolic pathway consists of: a. the citric acid cycle b. oxidative phosphorylation c. both a and b Which is the most energetic reaction? a. ATP + H_2O rightarrow ADP + Pi b. ATP + H_2O rightarrow AMP + PPi c. ADP + H_2O rightarrow AMP + Pi d. AMP + H_2O rightarrow adenosine + Pi The enzymes of the citric acid cycle are located in which part of the mitochondrion? a. the matrix b. the cristae c. the outer membrane d. the inner membrane Which is common to the structures of the three coenzymes CoA, NAD^+ and FAD? a. ATP b. ADP c. nicotinamide d. nicotinic acid When FAD is reduced to FADH_2 the hydrogen atoms are covalently bonded to: a. a carbon atom b. an oxygen atom c. a nitrogen atom d. two nitrogen atoms Riboflavin (one of the B vitamins) is part of the structure of: a. CoA b. ubiquinone c. NAD^+ d. FAD

Explanation / Answer

Ans – (c) The common catabolic pathway is a series of chemical reactions that take place inside our body which helps to oxidise food material in order to release energy to form ATP. ATP is used for various metabolic and regulation of body. Both citric acid cycle and oxidative phosphorylation consists of the catabolic pathway.

Ans b) ATP + H20 --------à AMP + PPi

This is the most energetic reaction as ATP is hydrolysed into AMP and during the breaking of the bond, it requires lot of energy and two phosphate molecules are released in the process. The energy released by hydrolysis or breakdown of ATP is used to power many metabolic and energy requiring process.

Ans- d) The process of citric acid cycle takes place in the matrix but the enzyme involved in CAA Isocitrate dehydrogenase is present in the inner mitochondrial membrane. It is produced from isomerisation of citrate in citric acid cycle.

Ans – a) The common factor in the structure of the three is they are all formed by ATP. An AMP moiety is transferred from ATP to nicotinate ribonucleotide to form desamido-NAD+. The final step is the transfer of the ammonia generated from the amide group of glutamine to the nicotinate carboxyl group to form NAD+. NADP+ is derived from NAD+ by phosphorylation of the 2-hydroxyl group of the adenine ribose moiety. This transfer of a phosphoryl group from ATP is catalyzed by NAD+ kinase. Flavin adenine dinucleotide (FAD) is synthesized from riboflavin and two molecules of ATP.

Ans d) Riboflavin is a part of structure of FAD as FAD is synthesized from riboflavin and two molecules of ATP. It is phosphorylated by ATP and produced FAD.