Blood is buffered by carbonic acid and the bicarbonate ion. Normal blood plasma
ID: 839207 • Letter: B
Question
Blood is buffered by carbonic acid and the bicarbonate ion. Normal blood plasma is 0.024 Min HCO?3 and 0.0012 M H2CO3 (pKa1 for H2CO3 at body temperature is 6.1).
Part A
What is the pH of blood plasma?
I got 7.4 for pH which is the correct answer
Part B
If the volume of blood in a normal adult is 5.0 L, what mass of HCl could be neutralized by the buffering system in blood before the pH fell below 7.0 (which would result in death)?
Part C
Given the volume from part B, what mass of NaOHcould be neutralized before the pH rose above 7.8?
Express your answer using two significant
Explanation / Answer
a) pH=pKa+log(salt/acid)
=6.1 + log(0.024/0.0012)
=7.4
b)when HCl is added, the base form (salt form ) reacts to give back carbonic acid. so let the number of moles of HCl added be x.so,
pH=pKa+log(Salt/acid)
or 7=6.1+ log((0.024*5 - x)/(0.0012*5 + x))
or x=0.008 moles
so mass=0.008*36.5
=0.29565 grams
c)let the moles of NaOH be x.so, in this case, the acid reats to give the base form.so,
7.8=6.1+ log((0.024*5 + x)/(0.0012*5 - x))
or x=0.0035 moles
so mass= 0.0035*40
=0.14 grams