Purine biosynthesis starts with the activation of a 5 carbon sugar. In this init
ID: 841334 • Letter: P
Question
Purine biosynthesis starts with the activation of a 5 carbon sugar. In this initial reaction, ribose 5-phosphate is converted into which of the following compounds?
PRPP (5- phosphoribosylpyrophosphate)
inosine monophosphate
glucose 6-phoshate
5- methyl thymidine
The regulation of PRPP synthetase is critical in the production of both purines and pyrimidines. This enzyme is inhibited under which of the following conditions?
When both GDP and ADP are elevated
When IMP is elevated
When CDP and TDP are elevated
When IMP is elevated
PRPP (5- phosphoribosylpyrophosphate)
inosine monophosphate
glucose 6-phoshate
5- methyl thymidine
The regulation of PRPP synthetase is critical in the production of both purines and pyrimidines. This enzyme is inhibited under which of the following conditions?
When both GDP and ADP are elevated
When IMP is elevated
When CDP and TDP are elevated
When IMP is elevated
Explanation / Answer
PRPP (5- phosphoribosylpyrophosphate)
When both GTP and ATP are elevated