CHAPTER 16 2009 Garland Science Publishing General Principles of Cell Signaling
ID: 86499 • Letter: C
Question
CHAPTER 16 2009 Garland Science Publishing General Principles of Cell Signaling proliferate. Factor F is 16-1 Cell lines A and B both survive in tissue culture containing serum but do not that cell line known to stimulate proliferation in cel line A. line A produces tor protein (R) cell line B. B does produce. To test the Cell receptor the presence of serum using DNA techniques. You then test all of your various cell lines in for recombinant summarized in Table Q16-1 their response to factor F. the results net Which of the following cannot be concluded from your resuls Ce line Cells in the table? cells do not (a) Binding of Factor F to its receptor is required for Factor F denot proliferate proliferation of cell line A. Factor F (b) Receptor R binds to Factor F to induce cell proliferation in receptor R Factor F cel proliferate (c) Cell line A expresses a receptor for Factor F (d) Factor F is not required for proliferation in cell line B list 16-2 For each following sentences, fill the blanks with the best word or phrase selected from the below. of the in word or phrase should be used only once. words phrases will be each o each other in various ways. A signal that must be relayed to the entire which produce hormones that are Cells can signal body is most efficiently sent carried throughout the body through the bloodstream. On the other hand, methods of cell signaling do not require the release of a secreted molecule and are used for very localized signaling events. During remains in the neighborhood of the secreting cell and thus acts as a signaling, the signal signaling converts electrical local mediator on nearby cells. Finally, impulses into a chemical signal. Cells receive signals through a which can be an integral membrane protein or can reside inside the cell phosphorylation epithelial G-protein amplification K channel contact-dependent receptor paracrine neuronal target 16-3 Rank the following types of cell signaling from 1 to 4, with l representing the type of signaling in which the signal molecule travels the least distance and 4 the type of signaling in which the signal molecule travels the largest distance. contact-dependent signaling paracrine signaling endocrine signaling neuronal signaling 6-5 Circle the phrase in each pair that is likely to occur more rapidly in response to an extracellular signal A. changes in cell secretion/increased cell division being synthesized changes in protein phosphorylation/changes in proteins changes in mRNA levels /changes in membrane potentialExplanation / Answer
16 option A
17. endocrine cells,contact dependent signalling,paracrine signalling, neuronal, receptor.
18. 1- contact dependent signalling.
2. Paracrine signalling.
3. Neuronal signalling
4. Endocrine signalling.
19. A. Changes in cell secretion.
B. Changes in proteins being synthesized.
C. Changes in mRNA levels