A critical reaction in the production of energy to do work or drive chemical rea
ID: 870986 • Letter: A
Question
A critical reaction in the production of energy to do work or drive chemical reactions in biological systems is the hydrolysis of adenosine triphosphate, ATP, to adenosine diphosphate, ADP, as described by ATP(aq) + H2O(l) rightarrow ADP(aq) + HPO2-4 (aq) for which Delta G degree r Times n = -30.5 kJ/mol at 37.0 degree C and pH 7.0. Calculate the value of Delta Gr Times n in a biological cell in which [ATP] = 5.0 mM, [ADP] = 0.80 mM, and [HP0422-] = 5.0 mM. Is the hydrolysis of ATP spontaneous under these conditions?Explanation / Answer
for the reaction
reaction quotient Q = [HPO4-2][ADP]/[ATP]
= 5*0.8/5 = 0.8 mM
= 8*10^-4 M
DGrxn = DG0rxn +RTlnQ
R = 8.314 j.K-1.mol-1
T= 37+273 = 310 k
= -30.5 + 8.314*310*2.303 log 8*10^-4
=?48.9 kj/mol
As DG is -ve . so that it is spontaneous.reaction.
Yes