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Could you please explain your answer ;) An emerging area of research in both aca

ID: 87933 • Letter: C

Question

Could you please explain your answer ;)

An emerging area of research in both academia and biotechnology is the innate immune response. Classic approaches to treating infection have focused on attacking the pathogen (e.g., antibiotics) or enhancing the host's adaptive immune response Exploiting the non-specific nature of the innate response could help protect individuals from a greater number/variety of pathogens. Furthermore, stimulation of the innate response would avoid the problem of antibiotic resistance in bacteria. You are an independent consultant hired by a new biotech start-up company interested in designing drugs that will stimulate innate immune responses as a way to fight infection. You are in the initial stages of the project-investigating possible innate immune pathways to target with the new therapeutics. One of your first ideas is to look at probiotics to enhance the host's normal microbiota The use of probiotics to stimulate the normal intestinal microbiota and promote general health has gained increasing popularity in recent years. There are several ways in which our normal microbiota protects us from infection. Which of the mechanisms below is not a protective mechanism of our normal microbiota? Which statement about protective mechanisms employed by normal microbiota is false? Normal microbiota consume nutrients. Normal microbiota spreading to locations where they are not normally found to prevent colonization from pathogens. Normal microbiota stimulate the second line of defense. Normal microbiota alter the pH of their environment.

Explanation / Answer

Answer:-option "b''normal microbiota spreading to locations where they are not normally found to prevent colonization from pathogens.

Normal Microbiota (Flora) play a role in the bodies first line of defense:-

**Normal microbiota help protect the body by competing with potential pathogens (microbial antagonism)

**Various activities of the normal microbiota make it hard for pathogens to compete.

• Consumption of nutrients makes them unavailable to pathogens
• Create an environment unfavorable to other microorganisms by changing pH
• Help stimulate the body's second line of defense .
• Promote overall health by providing vitamins to host.