Question #1: (0.8 point) Loss of a point for the heme group to attach to myoglob
ID: 893370 • Letter: Q
Question
Question #1: (0.8 point) Loss of a point for the heme group to attach to myoglobin by replacing His F8 with a Gly is an example of a change in primary structure that has severe consequences for protein function.
a.) True
b.) False
Question #2: (0.8 point) Which of the following is NOT a mechanism of enzyme regulation?
a.) Feedback inhibition by a product.
b.) Addition or removal of sulfate groups to amino acids with alcohol groups.
c.) Stimulation by a substrate or product.
d.) Proteolytic cleavage.
e.) Both b and c
Question #3: (0.8 point) Which of these is NOT true about the active site of an enzyme?
a.) It is composed of distinct amino acids that perform catalytic activities
b.) It often has a prosthetic group depending on the enzyme
c.) It is formed by the folding of the protein
d.) It is the site of binding of a competitive inhibitor
e.) It will always be affected by changes in the primary structure of the protein
Question #4: (0.8 point) Which is NOT true about the Km of an enzyme:
a.) is calculated as half of the maximal velocity of an enzyme
b.) is a hypothetical number that can only be predicted using experimental data
c.) is negatively affected by a competitive inhibitor
d.) is a measure of how tightly an enzyme binds to its substrate
e.) all of the above are true
Question #5: (0.8 point) Which is NOT true about Vmax:
a.) is the maximal velocity at which an enzyme can function
b.) is reduced by a non-competitive inhibitor
c.) is determined on a Lineweaver-Burke plot by taking the reciprocal of the y-intercept d.) is low for an enzyme with a low Km and high substrate affinity
e.) can be determined by multiplying the Km by 2
Explanation / Answer
Ans #1: Loss of a point for the heme group to attach to myoglobin by replacing His F8 with a Gly is an example of a change in primary structure that has severe consequences for protein function.
b.) False
Ans. #2: Of the following statements which does not associate with the mechanism of enzyme regulation,
c.) Stimulation by a substrate or product.
Ans. #3: Of the following the false statement about the active site of an enzyme,
e.) It will always be affected by changes in the primary structure of the protein
Ans. #4: The false statement about the Km of an enzyme,
d.) is a measure of how tightly an enzyme binds to its substrate
Ans. #5: The false statement for the Vmax of an enzyme,
d.) is low for an enzyme with a low Km and high substrate affinity