Consider two different antigens on red blood cells of wild type mice according t
ID: 91400 • Letter: C
Question
Consider two different antigens on red blood cells of wild type mice according to the pathway shown. All 3 genes are autosomal recessives and are unlinked. Two different true breeding mice have been isolated that do not make antigen1 or antigen2 (Both antigens are missing in each of these mice). A cross of these two mice produce F1 mice that make both antigens. What is the genotypes of the two parents Two of the F1 mice are crossed to one another. The possible phenotypes of the F2 are shown. The proportions of one class of the F2 are shown. Calculate the proportion of the remaining F2 classes. Antigen1+ antigen2+ Antigen1+ antigen2- Antigen1- antigen2+ Antigen1- antigen2-Explanation / Answer
1. The genotype of the two parents will be AA bb cc and aa BB CC.
2. Cross between two F1 will yield
Antigen 1+ + Antigen 2" = 27/64
Antigen 1+ + antigen 2- = 9/64
Antigen 1- + Antigen 2- = 1/64
Antigen 1_ + Antigen 2+ = 9/64