A DNA binding protein recognizes a specific 8 nucleotide sequence in DNA. Assumi
ID: 95895 • Letter: A
Question
A DNA binding protein recognizes a specific 8 nucleotide sequence in DNA. Assuming that the binding is perfectly specific, how many binding sites are expected to exist for it in human genomic DNA, which is composed of about 6 x 10^9 nucleotide pairs? What about if the protein forms a homodimer? Note that the target sequence can be oriented either way in the double stranded DNA
Explanation / Answer
Correct answer is :
e) About 200,000; about 3
Expected binding sites in the DNA is 200,000
When homodimer is formed the number of binding sites are 3