Since NAD+ and NADP+ are essentially equivalent in their tendency to attract ele
ID: 963617 • Letter: S
Question
Since NAD+ and NADP+ are essentially equivalent in their tendency to attract electrons, discuss how the two concentration ratios might be maintained inside cells at greatly differing values.
Check all that apply.
1.Because NAD+-dependent enzymes usually act to dehydrogenate (oxidize) substrates, an [NAD+]/[NADH] ratio greater than unity tends to drive reactions in that direction.
2.[NADP+]/[NADPH] ratio less than unity provide concentrations that tend to drive these reactions in the direction of substrate oxidation.
3. Because NADH-dependent enzymes usually act to hydrogenate (oxidize) substrates, an [NAD+]/[NADH] ratio greater than unity tends to drive reactions in that direction.
4. Because NAD+-dependent enzymes usually act to hydrogenate (reduce) substrates, an [NAD+]/[NADH] ratio greater than unity tends to drive reactions in that direction.
5. [NADP+]/[NADPH] ratio less than unity provide concentrations that tend to drive these reactions in the direction of substrate reduction.
6. [NADP+]/[NADPH] ratio less than unity provide concentrations that tend to drive these reactions in the direction of enzyme oxidation.
Explanation / Answer
The ratio of NAD+ and NADH are essential in the cell for proper functioning. The concentrations are maintained inside the cells at different values,
1. Because NAD++-dependent enzymes usually act to dehydrogenate (oxidize) substrates, an [NAD+]/[NADH] ratio greater than unity tends to drive reactions in that direction.
5. [NADP+]/[NADPH] ratio less than unity provide concentrations that tend to drive these reactions in the direction of substrate reduction.