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A. Rank the following compounds in order of decreasing acidity, putting the most

ID: 998540 • Letter: A

Question

A. Rank the following compounds in order of decreasing acidity, putting the most acidic first. why?

                                CH3OCH3          CH3CHO         CH3CH2OH          CH3COOH

                         I                        II                        III                            IV

B. Which of the following matches the molecules to the names of the functional groups? why?

CH3OCH3       Ether

CH3CONH2    Amine

CH3SH            Thiol

CH3CHO        Alcohol

C. Which of the following compounds has the highest boiling point? why?

D. Which of the following molecules are chiral? why?

I. 2-Chlorobutane

II. 3-Bromopentane

III. 2-Methylpropene

IV. 2-Bromo-3-methylbutane

E. What is the relationship between the following 2 components’? why?

Constitutional isomers

Identical

Stereoisomers

Not isomers, different compounds

F. Which of the following has the S Configuration? Why?

G. What kind of reaction does the conversion of A to B represent?

Acid-base reaction.

Elimination reaction.

Substitution reaction.

Addition reaction.

H. For the following reaction, use the identity of the alkyl halide and nucleophile to determine which substitution mechanism occurs. Then determine which solvent affords the faster reaction.

SN1, CH3OH

SN1, DMSO

SN2, CH3OH

SN2, DMSO

I. Which of the following is most likely to react as a nucleophile rather a base?

J. What is the most likely mechanism for the reaction below?

SN1

SN2

E1

E2

What is the best choice of reagent to accomplish the following transformation?

HCl

SOCl2, pyridine

Cl2

H3O+, H2O

Constitutional isomers

Identical

Explanation / Answer

A) Order of acidic nature : carboxylic acids > alcohols > aldehydes > ethers

Therefore, decreasing order of acidity is

IV > III > II > I

B)

CH3OCH3       Ether Correct

CH3CONH2    Amine wrong ( correct name = amide)

CH3SH            Thiol correct

CH3CHO        Alcohol wrong ( correct name = aldehyde)

E ) Stereo isomers

G) It is a addition reaction.

Because , H2O is added.

J) SN2

Because, the alkyl halide is primary.

Generally, primary alkyl halides undergo SN2 reaction.

K) ( Last question)

ans = SOCl2, pyridine

The best reagent to convert alcohils to alkyl halides = SOCl2, pyridine