Use the following information for questions 1 through 8 Most facultative anaerob

Question

Use the following information for questions 1 through 8 Most facultative anaerobic organisms that produce ethanol as a product use the glycolysis pathway followed by alcohol fermentation to produce ATP from glucose. The laboratory you work for has discovered an organism called E. hugdahlis that uses several reactions not found in the typical glycolysis pathway (reaction 1, reaction 2, and reaction 3 on the figure below). Only the three specified reactions utilize new enzymes, all other reactions utilize identical enzymes to typical glycolysis and alcohol fermentation. The new pathway is shown below: çO2 H+OH H20 20 reaction 2 reaction 1 HO-H glucose glucose-6-P reaction NAD NADH NADH HOH ATP ADP CH2OPO3 CO2 2-keto-3-deoxy 6-phosphogluconic acid H- OH CH2OPo32 reaction 3 NAD NADH CO2 acetaidehyde CO2 ethanol pyruvate NAD NADH ethanol acetaldehyde pyruvate+ - glyceraldehyde 3phosphate

Explanation / Answer

The regulation of glycolysis in general is brought about by the enzymes involved in the irreversible steps of the cycle, which are hexokinase, phosphofructokinase and pyruvate kinase. Here similarly step 1 & 2 are controlled by new reactions giving the same products hence the regulation can be expected to be similar.

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