Match each of the following antibacterial drugs with its mechanism of action (ca
ID: 102421 • Letter: M
Question
Match each of the following antibacterial drugs with its mechanism of action (can be used more then once)
Antibacterial drugs:
penicillins, sulfa drugs, bacitracin, beta-lactamases, aminoglycosides, cephalosporins
Mechanism of action:
a. prevent protein synthesis by binding to the 30S subunit
b. inhibit folic acid synthesis by competing for the enzyme that carries out this process
c. break the beta-lactam ring, which inactivated the beta-lactam drugs
d. inhibits the peptidoglycan synthesis by preventing the dephosphorylation of bacterprenol, which is the carrier molecule
e. inhibits the peptidoglycan synthesis by binding to the bacterial transpeptidiase
Explanation / Answer
Penicillin- inhibits the peptidoglycan synthesis by binding to the bacterial transpeptidase
Sulfa drugs- inhibit folic acid synthesis by competing for the enzyme that carries out this process
Bacitracin- inhibits the peptidoglycan synthesis by preventing the dephosphorylation of bacterprenol, which is the carrier molecule.
Beta lactamases- inhibits the peptidoglycan synthesis by binding to the bacterial transpeptidase
Aminoglycosides- prevent protein synthesis by binding to the 30S subunit
Cephalosporins- inhibits the peptidoglycan synthesis by binding to the bacterial transpeptidase