Care should be taken to avoid inhalation, eye contact, or ingestion of any of th
ID: 1043970 • Letter: C
Question
Care should be taken to avoid inhalation, eye contact, or ingestion of any of th CICu used in this experiment. Eye protection must be worn at all times, and students are encouraged to wear gloves. NaBH, NaBDs, and HCI are corrosive and the latter presents an inhalation hazard. Chronic exposure to CDCIs, CH2Cla, and methanol may present toxic and mutagenic hazards. Acetophenone and 1-phenylethanol are known to be flammable and to cause skin and eye irritation; it is reasonable to assume that this would still be true if one or more of their hydrogen atoms were replaced by deuterium. Methanol and hydrogen gas (liberated from the reaction of methanol with either NaBHs or NaBDs) are flammable. All the above hazards are significantly mitigated by the small scale of this reaction. Procedure: Reaction Place l mL of methanol and 50.0 ? L acetophenone into a 15 mL centrifuge tube. Add 20 mg of NaBHs of NaBD as described by the instructor (NOTE). Gently swirl to mix the contents and allow it to sit at room temperature 10 minutes. mixture is still in the centrifuge tube, use a Pasteur pipet and three 1 mL portions of methylene ecant into a pre-weighed 10-mL round-bottom flask, remove the solvent by rotary evaporation, Workup: Add i mL 10% HClou to the reaction mixture. Then, while the chloride to extract the product from this mixture. Dry the organic phase with anhydrous NazSO.4 then use a stream of air to remove any remaining traces of the solvent. Weigh to determine the yield Page 2 of 3 44)Explanation / Answer
12.96-12.75=0.21g or 210milligram is your weight of target compound ( actual yeild )
theoretical yield can be calculted by limiting reagent of your reaction ( reagent which controls the product yeild: limiting reagent)
theoretical yield devided by your 0.21g is percent yield