QUESTIONS Analgesic (pain relieving) tablets often contain one or more of the ac
ID: 1089760 • Letter: Q
Question
QUESTIONS Analgesic (pain relieving) tablets often contain one or more of the active ingredients listed in the table below: buprofen Aspirin Caffeine 0.60 0.45 0.24 0.08 A student separated the active ingredients present in an over-the-counter pain reliever usin g chromatography. The chromatogram shown below was obtained using silica gel as the stationary phase and ethyl acetate as the mobile phase. Use this chromatogram and the information in the table above to answer the questions that follow. (Note: Make your measurements to the centers of the spots.) a. How many active ingredients were present in tme tablet b Calcvlate tne Re Value of the spot closest to tme Sample lne torigin). Show your work, C. Calculate tme Re valve of tme spot closest to tne solvent front. Show your wark. d fwe tmu namas of the active ingredients present in mis analces ic taoletExplanation / Answer
a. There are two active ingridients as there are two spots on the silica sheet.
b. Here we have to calculate the Rf value of the lower spot.
c. here we have to find rf of the upper spot. follow steps given in previous parts.
d. based on the rf value obtained, match it with the table given. that will give the name of active ingridient.
NOTE: i am not able to give exact numbers/ calculations here because the image provided is not to scale.