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In Drosophila, singed bristles (sn) and carnation eyes (car) are both caused by

ID: 11907 • Letter: I

Question

In Drosophila, singed bristles (sn) and carnation eyes (car) are both caused by recessive alleles. The wild-type alleles (sn+ and car+) are responsible for straight bristles and red eyes, respectively. A sn+ car female is mated to a sn car+ male and the F1 progeny are testcrossed, resulting in the following distribution of offspring:

sn car         42
sn car+       65
sn+ car       55
sn+ car+     38

Total 200

What is the value of X2 for a test of the hypothesis that the sn and car genes are unlinked?

Explanation / Answer

sn car 42
sn car+ 65
sn+ car 55
sn+ car+ 38

Total 200

singed bristles (sn) and carnation eyes (car) are both caused by recessive alleles

alleles (sn+ and car+) are responsible for straight bristles and red eyes

              sn+ car    female       x        sn car+ male

offspring-           sn+/sn   car/ car+ -----------------F1

TEST CROSS

sn+/sn   car/ car+              X            sn/sn   car/ car            

EXPECTED RATIO------------------ 1:1:1:1

sn car+ 65
sn+ car 55
sn+ car+ 38

OBSEREVED (O)

EXPECTED(E)

O-E

(O-E)2

(O-E)2/E

sn car

42

50

-8

64

1.28

sn car+

65

50

-15

225

4.5

sn+ car

55

50

5

25

0.5

sn+ car+

38

50

-12

144

2.88

200

9.16

X2= SUM OF (O-E)2/E
What is the value of X2 for a test of the hypothesis that the sn and car genes are unlinked?

the value of X2 for a test of the hypothesis that the sn and car genes are unlinked= 9.16

IT IS MORE THAN THE TABLE VALUE, SO THE hypothesis IS REJECTED,

THE ALLES ATE LINKED

OBSEREVED (O)

EXPECTED(E)

O-E

(O-E)2

(O-E)2/E

sn car

42

50

-8

64

1.28

sn car+

65

50

-15

225

4.5

sn+ car

55

50

5

25

0.5

sn+ car+

38

50

-12

144

2.88

200

9.16