The mouse X chromosome carries a gene specifying coat color (Black is dominant;

Question

The mouse X chromosome carries a gene specifying coat color (Black is dominant; vs agouti
which is recessive) and a gene which when deficient causes a recessive neurological disorder
(twitchy). These two genes are linked at 12 m.u. Two mice collected from the wild, an agouti
male (M) and a black female (F) (both non-twitchy), are mated, producing an F1 brother and
sister. The sister is then crossed back to her father generating four progeny in the F2:
P M agouti x black F
F1 F black + twitchy M
F2 1) M black & twitchy
2) M agouti
3) F black
4) F agouti
If F2 females 3) and 4) are mated, what are the probabilities that they produce twitchy males
(two answers required).

Explanation / Answer

Mated to what? What is the genotype of the male?

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