Consider three linked locis, SNP01, SNP02, and SNP03. The alleles at the respect

Question

Consider three linked locis, SNP01, SNP02, and SNP03. The alleles at the respective loci are A,a (SNP01), B and b (SNP02), and C and c (SNP03). Given the following table of haplotype counts: Haplotype counts for three loci Phenotype Number of Observed haplotypes ,What SNP is in the middle? A. SNP03. B. SNP02 is between SNP02 and SNP01. C. All SNPs have 0 recombination among them. D. SNP02. E. SNP01.

thank you

Haplotype counts for three loci Phenotype Number of Observed haplotypes Abc 1 aBC 1 abc 455 AbC 24 ABC 490 ABc 26 aBc 15 abC 28

Explanation / Answer

Answer - E

Parent
ABC - 490
abc - 455

Double cross over
Abc    1
aBC    1

The DCO the the cross between a and A gives a parental strand A B C.
So, the order is worng.
The order must be B A C.

If we dco the parents B A C

             b   a   c

we get the DCO pattern now.

So, SNP01 is present in the middle.

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