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Submit your homework only in ppt/word/pdf format (We are not responsible for any

ID: 166373 • Letter: S

Question

Submit your homework only in ppt/word/pdf format (We are not responsible for any other file format that are not supported by blackboard; for example: pages) Do not submit hand-written assignment or images taken using your cell phone. Type your answers and if required provide screenshots and proper annotations. Save your homework as Lastmane_Firstname_Homework#.pdf Answer the following three questions a. Write an mRNA sequence that would include a start codon and code for a 6-amino acid peptide (specify). Add a stop codon. b. Write out the same sequence except with a synonymous mutation (specify mRNA and peptide sequences). c. Write it again with a non-synonymous mutation (specify mRNA and peptide sequences).

Explanation / Answer

A. 5'AUGTCCGATATATGGCAACCCUAA3'

5'-start-S D I W Q P -stop-3'

B. 5'-AUGTCAGATATATGGCAACCCUAA-3'

5'-start-S D I W Q P -stop-3'

C. 5'-AUGTCAGATCTATGGCAACCCUAA3'

5'-start-S D L W Q P-stop-3'

Note:

S serine

D aspartate

I isoleucine

W tryptophan

Q glutamine

P proline

L leucine