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An oncogene is produced from a _________ that has acquired a ___________ a. Prot

ID: 167063 • Letter: A

Question

An oncogene is produced from a _________ that has acquired a ___________ a. Proto-oncogene, loss-of-function mutation b. Proto-oncogene, gain-of-function mutation c. Tumor-suppressor gene, loss-of-function d. Tumor suppressor gene, gain-of-function mutation Check all that apply. Select the factors that would indicate that a disease had a genetic, rather than an environmental, cause. Check all that apply. ______ The disease spreads from person to person. _______ The disease has a specific age of onset. ______ There is a high level of the disease's concordance among monozygotic twins. ________ The disease does not spread to people sharing similar environmental situations. Transposable elements (TEs) are associated with a diverse array of human diseases. Explain why this may be the case. Interestingly, of the human diseases caused by TEs, there appears to be an overrepresentation of diseases identified that are X-linked. Having taken BBIO 360, provide one possible reason for bias in this observation, (more than one possible answer) A genetic predisposition to developing cancer is usually inherited as a dominant trait. At the level of cellular function, are the alleles involved actually dominant? Explain why some individuals who have inherited these dominant alleles do not develop cancer during their lifetimes. Is this mitotically heritable, and is this meiotically heritable?

Explanation / Answer

According to chegg minimum protocol i need to answer first full question but i will try to answer more

Protooncogene that has accuired a gain of function mutation ..... Example gain of function in ras protein ...

The disease has specific age of onset

There is high level of disease concordance among monozygotic twins

The disease does not spread among persons sharing similar environmental conditions ...

Transposable elements can cause insertional mutagenesis by randomly moving along genome this insertional mutations in functionally important regions might be the cause for diverse array of human diseases

Hope it helps ... Feel free to discuss ... Regards