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An oncologist has two patients (Patient A and Patient B) with renal cell carcino

ID: 264058 • Letter: A

Question

An oncologist has two patients (Patient A and Patient B) with renal cell carcinoma.

The metastatic signature of patient A suggests her tumor is not invasive and that she has a

good prognosis. In contrast, Patient B has a tumor with a metastatic signature that

indicates a poor prognosis. Aggressive levels of either chemotherapy and/or radiation

therapy will be necessary to treat her tumor.

A. List and describe the activities of two factors that would contribute to the poor metastatic signature of patient B.

(10 pts.)

B. List two factors (not described in A, above) whose presence (or absence)

contribute to the good metastatic signature of patient A.

(10 pts.)

Explanation / Answer

An oncologist has two patients (Patient A and Patient B) with renal cell carcino