If there was a mutation in the DNA sequence below giving the following DNA seque

Question

If there was a mutation in the DNA sequence below giving the following DNA sequence,

-GATTGACCGTAA-
-CTAACTGGCATT-

what would be the resulting mRNA and peptide sequence?

Explanation / Answer

the mRNA is "mirror" to DNA ( A->U, T->A, G->C and C->G) so the mutated DNA gives -CTAACTGGCATT---> GAUUGACCGUAA when it should be ( not mutated) -GATTGACCGTAA----> CUAACUGGCAUU the Aminoacid sequence can be read with genetic code table and the mRNA is read in triplets ( 3 basepairs at a time) for example http://andersonlab.qb3.berkeley.edu/Tutorials/Basic_Molecular_Biology_files/image006.jpg the mutated gives the following aminoacid sequence: GAU UGA CCG UAA-->asp,stop. ( UGA --> stop triplet and that is as far as the translating goes) while it should be CUA ACU GGC AUU--> leu,thr,gly,ile.

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