The representative chromosomes of animals and the initial crosses in a QTL mappi
ID: 167209 • Letter: T
Question
The representative chromosomes of animals and the initial crosses in a QTL mapping project for body size are shown in Panel A. The chromosome material from the largest purebred line are represented by the black regions, the other pure bred line used in the experiment is represented by the white regions. Panels B,C, D and E show the karyotypes representative of the largest animals from two different populations that were created for QTL mapping. From left to right the homologous chromosome pairs are 1,2, and 3.
a) The animals from the first QTL mapping population are represented by panels B and C. The animals from the second QTL mapping population are represented by panels D and E. Explain the difference between the two approaches used for QTL mapping in these two experiments.
b) Between the mapping population that includes panels B & C and the mapping population that includes panels D & E, which one would be faster to breed? Explain your reasoning.
c) The largest animals from their respective populations are represented by the cromosomes in panels B-E. Which chromosomes are most likely to have genes that affect body size and what are some potential location/s of QTL's? Explain your reasoning.
Pure line A Pure line B o oo oo ooExplanation / Answer
a)The difference between panels b and c fromthe panels d and e is that in panels B.C thelargest purebred line is present at different locations while in D AND E it is present at the same location in both the bodies as represented
b)The B,C panel is faster to breed because the purebred line is scattered which can increase from both sides unline in panels D,E where they are present at the same locations.
c)The chromosomes present in C AND D affect the size as the purebred region keeps changing and the purebred region increases from C to D which affects the size and leads to an increase .