Matching DNA repair - Answers may be used more than once or not at all In E. col
ID: 176136 • Letter: M
Question
Matching DNA repair - Answers may be used more than once or not at all In E. coli the MutS, MutL and Mut H mediate this DNA damage repair Nucleotide Excision Repair Mutations in this pathway can cause Xeroderma pigmentosum Mismatch Repair Mutations in this pathway can cause Hereditary Base-Excision Repair Non-polyposis colorectal carcinoma Homologous recombination Recognizes and repairs more bulky lesions in the DNA Mediates repair through an intermediate pathway that includes an Abasic (AP) site Is most commonly used to repair double strand DNA breaks Describe the difference between DNA damage and a mutation. Are they the same thing?Explanation / Answer
12. DNA mismatch repair: in E.coli Mut S, Mut L, Mut H mediates this DNA damage repair.
Nucleotide excision repair: mutations in this pathway can cause Xeroderma pigmentosum. Enzymes involved in NER are mutated and results in the condition of Xeroderma pigmentosum.
Mismatch repair: mutation in this pathway can cause hereditary non polyposis colorectal carcinoma.
Nucleotide excision repair: recognize and repair more bulky lesions in DNA. It removes DNA damage which has been induced by ultraviolet light.
Base excision repair: mediates repair through an intermediate pathway that includes an AP site.
Homologous recombination: is most commonly used to repair double strand DNA breaks.