Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

Show all the types of RNA (SNO, SNRP, mi, m, si, t, r, nc others) and explain th

ID: 178754 • Letter: S

Question

Show all the types of RNA (SNO, SNRP, mi, m, si, t, r, nc others) and explain their functions in the central dogma.

Illustrate some molecular functions and catalytic activities of the tetrahymena hammer head ribozyme.

Show the peptide synthesis (peptidyl transferase) activity of domain V of 23S rRNA; A2486 in terms of the P, E, A sites along with the small subunit and mRNA.

What are intron exon borders in eukaryotic RNA?

What are the types of introns

Show RNA processing.

Show the structure of an ncRNA gene.

Show the mechanism of self splicing introns.

Compare and contrast introns to other mobile genetic elements

How might their functions relate to Chemical evolution and the modular nature of exons in Eukaryiotic proteins?

What might be the relationship between Eukariotes having modular intron/exon genes, rapid evolution and jumping genes?

Explanation / Answer

1) Three main types of RNA : mRNA (Messenger), tRNA (Transfer), rRNA(Ribosomal)

Messenger RNA: Encodes amino acid sequence of a protein or polypeptide during translation. Genetic information of DNA is transcribed into mRNA during transcription.

Transfer RNA: During translation, brings aminoacids to ribosomes.

Ribosomal RNA: It helps in binding of mRNA to ribosomes.

Other types of RNA:

siRNA : Small Interfering RNA regulates protein expression.

miRNA: Micro RNA also regulates protein expression.

snRNA: Small nuclear RNA is involved in splicing of introns.

hnRNA: Heterogeneous RNA is the immediate product of transcription and then it is processed to mature mRNA

snRNP: snRNA complexed with specific proteins is called as small nuclear ribonucleoproteins (RNP)

SNO: A large group of snRNAs are called are small nucleolar RNA (SNO) and it is involved in guiding chemical modifications of important RNAs