For the following coding DNA sequence: CAACATGTTATGTGGGAACATGGACCCAGAATGTGACTTCA

Question

For the following coding DNA sequence: CAACATGTTATGTGGGAACATGGACCCAGAATGTGACTTCATCACCCAGCTGAGAGAGGATGAGAGTGCCTGTCTACAAGCAGCAGAGGAGATGCCCAACACCACCCTGGGCTGCCCTGCGACCTGGGATGGGCTGCTGTGCTGGCCAACGGCAGGCTCTGGCGAGTGGGTCACCCTCCCCTGCCCGGATTTCTTCTCTCACTTCAGCTCAGAGTCAGGGGCTGTGAAACGGGATTGTACTATCACTGGCTGGTCTGAGCCCTTTCCACCTTACCCTGTGGCCTGCCCTGTGCCTCTGGAGCTGCTGGCGTGAGGAGG

a. Determine the mRNA and amino acid sequences that this DNA codes for

b. In mutant X, base 35 is C instead of G.
What would be the resulting amino acid sequence, and would this protein likely be functional? Justify your answers.

c. In mutant Y the first G of the sequence is deleted. What would be the resulting amino acid sequence, and would this protein likely be functional? Justify your answers.

Explanation / Answer

1) mRnA sequence

GUU GUA CAA UAC ACC CUU GUA CCU GGG UCU UAC ACU GAA GUA GUG GGU CGA CUC UCU CCU ACU CUC ACG GAC AGA UGU UCG UCG UCU CCU CUA CGG GUU GUG GUG GGA CCC GAC GGG ACG CUG GAC CCU ACC CGA CGA CAC GAC CGG UUG CCG UCC GAG ACC GCU CAC CCA GUG GGA GGG GAC GGG CCU AAA GAA GAG AGU GAA GUC GAG UCU CAG UCC CCG ACA CUU UGC CCU AAC AUG AUA GUG ACC GAC CAG ACU CGG GAA AGG UGG AAU GGG ACA CCG GAC GGG ACA CGG AGA CCU CGA CGA CCG CAC UCC UCC

Amino acid sequence

val-val-gln-tyr-thr-leu-val-pro-gly-ser-tyr-thr-glu-val-val-gly-arg-leu-ser-pro-thr-leu-thr-asp-arg-cys-ser-ser-ser-pro-leu-arg-val-val-val-gly-pro-asp-gly-thr-leu-asp-pro-thr-arg-arg-his-asp-arg-leu-pro-ser-glu-thr-ala-his-pro-val-gly-gly-asp-gly-pro-lys-glu-glu-ser-glu-val-glu-ser-gln-ser-pro-thr-leu-cys-pro-asn-met-lle-val-thr-asp-gln-thr-arg-thr-arg-glu-arg-trp-asn-gly-thr-pro-asp-gly-thr-arg-arg-pro-arg-arg-pro-his-ser-ser

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