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Poliovirus is a naked +RNA virus with an icosahedral capsid. It infects lymphoid

ID: 180848 • Letter: P

Question

Poliovirus is a naked +RNA virus with an icosahedral capsid. It infects lymphoid cells and neurons and can cause paralysis. If you use a light microscope to look at the cerebral spinal fluid of someone infected with polio, what do you expect to see?

host cells and many viral particles in the fluid

host cells with a few viral particles in the fluid

many viral particles coating the cell membrane of host cells

only host cells

a.

host cells and many viral particles in the fluid

b.

host cells with a few viral particles in the fluid

c.

many viral particles coating the cell membrane of host cells

d.

only host cells

Explanation / Answer

b). host cells with a few viral particles in the fluid.

In the people infected with polio, the CSF contains less number of viral particles, but more number of white blood cells. As the polio virus is a naked virus, it do not coat the cell membrane of the host cells.