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Consider the tryptophan codon: 5\'-UGG-3\'. It is recognized by a tRNA whose ant

ID: 181421 • Letter: C

Question

Consider the tryptophan codon: 5'-UGG-3'. It is recognized by a tRNA whose anticodon is 5'-CCA-3'. Because of wobble pairing, the tryptophan codon could also be hypothetically recognized by an otherwise identical tRNA with anticodon sequence 5'-UCA-3'. However, such a hypothetical tRNA does not normally exist. Why?

This hypothetical tRNA would be charged with cysteine instead of tryptophan leading to incorporation of a wrong amino acid

This hypothetical tRNA would also recognize a cysteine codon 5'-UGC-3' leading to incorporation of tryptophan instead of cysteine

The hypothetical tRNA would recognize the stop codon 5'-UGA-3' leading to longer-than-normal proteins

This hypothetical tRNA would be charged with cysteine instead of tryptophan leading to incorporation of a wrong amino acid

This hypothetical tRNA would also recognize a cysteine codon 5'-UGC-3' leading to incorporation of tryptophan instead of cysteine

The hypothetical tRNA would recognize the stop codon 5'-UGA-3' leading to longer-than-normal proteins

Explanation / Answer

Answer: Option C

The hypothetical tRNA would recognize the stop codon 5'-UGA-3' leading to longer-than-normal proteins