Please dont answer this question with the answer to a different problem that is
ID: 183830 • Letter: P
Question
Please dont answer this question with the answer to a different problem that is similar. This is the fourth time submitting this question and people keep giving me answers to similar but different but different questions.
In muscle tissue, the ratio of phosphorylase a to phosphorylase b determines the rate of conversion of glycogen to glucose 1-phosphate Classify how each event affects the rate of glycogen breakdown in isolated muscle tissue Increased rate Decreased rate addition of phosphatase PP1 addition of a kinase inhibitor [ATP] exceeds [AMP] treatment with insulin addition of a phosphatase inhibitor No change addition of phosphorylase b kinase AMP allosteric binding activates phosphorylase bExplanation / Answer
In muscles glycogen cleaves in to G6P in the presence of glycogen phosphorylase. G6P forms G1P in the presence of phosphoglucomutase. The ratio of phosphorylase a (active) to phosphorylase b (less active) determines the conversion of glycogen to glucose 6-phosphate and to G1P.
Glycogen breakdown increases by treating with the kinase and ATP, by which glycogen phosphorylase becomes more active, phosphorylated form, phosphorylase a.
Glycogen breakdown decreases with the treatment of phosphatase PP1, which converts the active phosphorylase a to the less active phosphorylase b.
Phosphorylase b (less active) converts into phosphorylase a (more active) by kinase which increases the glycogen breakdown. This phosphorylase kinase, is activated by epinephrine which synthesize the cyclic AMP.