Can someone help with the question? Thanks! Question 2 (5 points) Specialized ne

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Can someone help with the question? Thanks!

Question 2 (5 points) Specialized neurons that aid in the sense of smell express GPCR molecules that can detect specific odorant molecules. These GPCR molecules contribute to a signaling cascade that eventually leads to changes in membrane potential within the neuron due to movement of ions across the membrane. A model for how this signaling cascade works is shown below. CNG is a ligand-gated ion channel Imagine you have cultured neurons in the lab and you have a drug that specifically locks GTPase proteins in the GDP-bound state. What would you expect to happen if you treated your cells with odorant in the presence of the inhibiting drug? OR CNG Cl-channel AC3 ATPO 0

Explanation / Answer

The correct answer is option A.

this is because G-protein usually binds with receptor when they are deactivated. Due to the presence of inhibitor, even after recognising the receptor the G-protein does not get activated. This prevented all other steps to occur.

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