Acetyl-CoA Condensation CoA-SH citrate synthase Ho CH2-COo Oxaloacetate CH2-cO0
ID: 197865 • Letter: A
Question
Acetyl-CoA Condensation CoA-SH citrate synthase Ho CH2-COo Oxaloacetate CH2-cO0 Dehydration Citrate Dehydrogenation Citric acid cycle H20 malate aconitase oo- dehydro- genase coo HO-CH Malate CH2 cis-Aconitate C-COO COO C-COO H20 Hydrationfu fumarase 2b NADH aconitase H20 Hydration CH2-coo Fumarate CH H-C-COO ADH Isocitrate HC HO isocitrate I succinate dehydrogenase COO dehydrogena / coo- Oxidative decarboxylation 6 -ketoglutarate dehydrogenase complex Dehydrogenation CH2-coo CO2 succinyl-CoA synthetase 2-COO COO CH2-COo Succinate 0 CoA-SH -Ketoglutarate CoA-SH GDP C-S-CoA (ADP) ATP/ CO2 Oxidative Substrate-level phosphorylation Succinyl-CoA decarboxylationExplanation / Answer
Ans 1) Option D will be the answer.
Explain- The NAD+ dependent isocitrate dehydrogenase requires Mg+ or Mn+ cofactor which catalyses the oxidation of the secondary alcohol (Isocitrate) to a ketone (Oxalosuccinate) followed by the decarboxylation of the carbonyl group beta to ketone. This decarboxylation forms the release of CO2.
Ans 2) Option C will be the answer.
Explaination:- Pyruvate is converted into Oxaloacetate by the enzyme Pyruvate Carboxylase. It is the most important anaplerotic reactionn or filling up reaction.
ns 3) Option A is correct.
The Co-A group of Succinyl Co-A is replaced by Pi to form Succinyl Phosphate and Co-A . The formmation of phosphoryl-His. a high energy intermediate and transfer of the phosphoryl group to GDP forming GTP.