Incorrect 0/ 5 pts Question 2:3 MOLECULAR BIOLOGY OF THE MARVELVERSE DR. XAVIER,

Question

Incorrect 0/ 5 pts Question 2:3 MOLECULAR BIOLOGY OF THE MARVELVERSE DR. XAVIER, who has a PhD in molecular genetics, wants to bring you on board as a researcher to better understand the changes that lead mutants to their super abilities. In this SECOND part of the exam you demonstrate your expertise in the molecular biology of DNA repair to speculate about the capabilities of several well known mutants Xmen heroine Rouge's ability manifests as a sucking away of life force when she touches another human. You hypothesize that her superpower causes double strand breaks to form in her opponent's DNA. Since her ability manifests whenever she touches another person you further hypothesize that her power does not only affect those cells that are in S phase. Which protein complexes might you investigate first? DNA glycosylase BRCA1 RAD51 Ku70-Ku80 heterodimers

Explanation / Answer

I would investigate first ku70/ku80 heterodimer, as they recognise DNA double-strand breaks during non-homologous end joining. Mutation in them can cause DNA breaks, therefore is very important to investigate them.

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