Imagine it\'s the late 1800\' compositin structure and organization of cells and
ID: 203195 • Letter: I
Question
Imagine it's the late 1800' compositin structure and organization of cells and particularly cell membranes. The current state of knowledge at (De Weer, 2000): s and an exciting time in cell biology as little is known about the biochemical and physical in part on work conducted on erythrocytes (red blood cells) as early as 1773, can be summarzed as te of knowledge at this Living cells contain fluid This fluid is separated from the external environment by a visible membrane of unknown composition and .The volume of this fluid can change depending upon the nature of the fuid in which cells are structure change in volume can cause the cell to either shrink, swell or sometimes burst (lyse). . The membrane is permeable to water but apparently not generally to solutes An example of the kind of data that supported the contention that cell membranes are impermeable to solutes appears in Figure I Jacobs, 1931). Consider the data and answer the questions that follow. 350 300 Sodium ion concenraton 200 concertraion per 100 oc) Figure 8. Average concentration of dissolved, left) sodium (Na") and right) potassium (K') ions in live dog erythrocytes (dark gray. mg per 100 cc) and the blood plasma in which the erythrocytes are immersed (light gray, mg per 100 cc). N-7. Error bars are 95% confidence intervals. Data from Kerr (1929). I. Please describe what the data, in Figure 8 above, suggest about the concentration of a) sodium and b) potassium ions inside dog erythrocytes relative to the surrounding plasma. 2. Data from other mammal species reveal a pattern similar to that above (Jacobs, 1931). Please explain why data like suggest that cell membranes are impermeable to (at least some) solutes 3. What would you expect the figures above to look like if the membrane of erythrocytes was permeable to these two solutes? You may wish to draw them hereExplanation / Answer
As per conditions given in question very little knowledge is about biochemical and physical composition structure and organization of cells.
As per fig. 8 average concentration of dissolved Sodium Na+ and Potassium K+ in live dog erythrocytes
In case of Potassium K+ , concentration in plasma is 20 mg per 100cc and that of erythrocytes is 50 mg per 100cc which means that Potassium K+ concentration in erythrocytes is more than Sodium Na+ concentration in plasma.
Membrane of erythrocytes is less permeable to Sodium Na+ while it is more permeable to Potassium K+
In case of Sodium Na+ permeability of Membrane of erythrocytes is 20 % less than plasma
In case of Potassium K+ permeability of Membrane of erythrocytes is 150% more than plasma