Please solve those question and tell me why. Thank you. Hi It Runs in the Family

Question

  

Please solve those question and tell me why. Thank you.

Hi It Runs in the Family hen more than one individual in a family is afflicted with a disease, it suggests that the disease might be inherited. A basic method for determining the pattern of inheritance of any trait, including a disease, is to look at its occurrence in several individuals within a family, spanning as many generations as possible. Family history information is usually combined with information from medical tests, increasingly including genetic tests. From family history and medical test results, a physician, genetic counselor, or researcher can draw a pedigree. A pedigree is simply a family tree that uses a particular set of standardized symbols. Introduction to Pedigree Symbols . Males are represented by squares. . Females are represented by circles. Filled symbols show individuals who exhibit the trait in question. . A horizontal line between two symbols represents a mating. A vertical line descends from parents to a horizontal line shared by all their offspring. . A diagonal line through a symbol indicates that person is deceased. . Roman numerals (I, , 111, ) represent generations. Arabic numerals (1, 2, 3,..) represent the birth order of siblings. Specific combinations of numerals (like II-3) uniquely identify each individual in the pedigree. Many pedigrees do not include numerals. 01. Individual II-5 in the pedigree shown to the right is A) A male who does not exhibit the I trait. B) A father C) Has three affected siblings. D) All of the above. Now let's look at a larger pedigree.

Explanation / Answer

Q1. Individuals II-5 in the pedigree shown to the right is:
Correct option:

Explanation: If we look at the pedigree chart, in generation II individual 5 (male) does not exhibit the trait is a father of one female and one male and have three affected siblings of his parents.
Q2. The disease is very severe and strikes early in childhood
Correct option:

Q3. This large pedigree shows a dominant trait
Correct option:

Q4. What might account for the increasing severity and earlier onset of SCA1 each generation?
Correct option:

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