Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

Please answer the whole page Pedigree 4 - Below is a pedigree showing the patter

ID: 209958 • Letter: P

Question

Please answer the whole page

Pedigree 4 - Below is a pedigree showing the pattern of irhertance of a rare genetlic condition in a particular family 9 101 2 10 111213 1. What is the most likely mode of inheritance for the trai? uthomalin 2. Provide as much as possible the genotype of each of the following a. b c. l-1 1-2 g. IV-2- 3. What is the probability that individual -8 is 4. What is the probability that individual ill-1 is 5. If IV-2 heterozygous? heterozygous? mm and IV-5 were to have a chilid together, what wouid be the prohability of a being affected?

Explanation / Answer

1. The mode of inheritance for the trait = Autosomal Dominant.

Explaination:

2. Genotypes:

a. I-1 = XaYa

b. I-2 = XAXa

c. II-2 = XaXa

d. III-8 =  XaXa

e. III-9 = XAYa

f. IV-2 =

3. Probability of III-8 is heterozygous = 0% because it is an affected individual and it has a genotype of XaXa. So it is a homozygous.

4. Probability of III-1 is heterozygous =

5. probability of affected offsprings of the parents IV-2 and IV-5 = It is 0% because when IV-2 with genotype XaYa mates with IV-5 with genotype XAXA, there offsprings will be normal and not affected with heterozygous genotypes.