Please answer the whole page. Pedigree 2 -Below is a pedigree showing the patter

Question

Please answer the whole page.

Pedigree 2 -Below is a pedigree showing the pattern of inheritance of a rare genetic condition in a particular family 1 2 3 4 5 111 TO 2 34 5 6 7 9 10 11 12 9 10 1. What is the most likely mode of inheritance for the trait?_x-linkd si 2. 3. Provide as much as possible the genotype of each of the following a. b. 1-1 C. 1-2 f. IV-4 g. V-5 4. What is the probability that individual IV-3 is heterozygous? 5. If V-2 and V-4 were to have a son together, what would be the probability of it being affected?

Explanation / Answer

1. X - linked recessive disorder

More males than females are affected, It is never passed from father to son, All daughters of affected fathers are carriers.

3.

b. I-1 XAXa
c. I-2 XAY
d. II-2 XAXa
e. II-4 XaY
f. IV-4 XAXa
g. V-5 XaXa

4. III-1 = XAY III-2 XAXa
P = 1/2 X 1/2 = 1/4

5. V-2 XAXa V-4 XAY
P = 1/4

                

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