How is q2, p2 and 2pq determined. what are the calculations. all the other calcu
ID: 214439 • Letter: H
Question
How is q2, p2 and 2pq determined. what are the calculations. all the other calculations are show.
Hypothetical Sample of Drosophila SO S1 S2 S3 Phenotype Frequencies (Counts) Total Mutant Wild 120 60 60 200 45 155 200 15 185 Phenotype Frequencies Proportion Mutant Wild 0.50 0.50 0.225 0.775 Observed Allele Frequency Proportion allele q allele p 0.50b 0.50 0.474c 0.525 q2 p2 2pq 0.225 0.286 0.4977 Change in Allele Frequency allele q allele p ---0.948e Fitness(W) S1 S2 allele q allele p 0.9039 1.00 Count of Phenotype/ Total Individuals Counted Remember, the phenotypes are homozygous!! Square Root of Mutant Phenotype Proportion "Frequency of p = 1 - °Change in q = q1/0 Change in p = p1/po Lowest Change/Highest Change; Highest Change is 1.0 (W) 0.948/1.050.9028 (Wp) = 1.05/1.05 = 1.00Explanation / Answer
When there are two alleles in a population, p represents the dominant allele frequency and q represents the recessive allele frequency.
When the population follows Hardy Weinberg principle, the equation is:
p2 + q2 +2pq = 1
where, p2 represents the frequency of homozygous dominant allele, q2 represents the frequency of homozygous recessive allele and 2pq represents the frequency of heterozygous allele.
So, by using the equation p + q = 1, the value of p and q is determined.