Part 1: Enzyme Active Sites Shown below are active sites from several protein-ba
ID: 220456 • Letter: P
Question
Part 1: Enzyme Active Sites Shown below are active sites from several protein-based enzymes in the human body. For each of them identify the amino acids present (the side chains are shown) and the type of interactions/intermolecular forces (see page 573 of the textbook) possible for each amino acid within the active site in the table provided then answer the question if there is ore NHa NHa 5 Site Amino Acid Interactions 1. Which of the two molecules shown next to the enzyme would you expect Enzyme 1 to have substrate and why? Be specific! [1 pt]Explanation / Answer
1) Arginine is the amino acid and in their catalytic site they can form hydrogen bond or amide bond with their substrate molecules.
2) This R group is of Histidine amino acid and it's catalytic active site has a protonated Histidine residue that can acts like a general acid during catalytic reactions.
3 and 4) This a side chain of Arginine amino residue. The side chain of Arginine amino acid interact with the substrate molecules by forming hydrogen bond or amide bond.
5) This side chain could be of tryptophan amino acid residue. They basically interact with their substrate molecules through non covalent interaction to perform the catalysis of the reaction .