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Mastering Genetics: Chapter nine Google Chrome Secure https://session.masteringg

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Question

Mastering Genetics: Chapter nine Google Chrome Secure https://session.masteringgenetics.com/myct/itemview?offset next&assignmentProblemID; 494 1909 General Genetics Help I Close Chapter nine Problem 9.3 previous l 34 of 36 l next Problem 9.3 Several lines of experimental evidence pointed to a triplet genetic code. Part A Identify three pieces of information that supported the triplet hypothesis of genetic code structure. Select the three correct answers. n vitro translation of RNA composed of a dinucleotide repeat produced polypeptides with three alternating amino acids, as expected from a triplet code. n vitro translation of RNA composed of a dinucleotide repeat produced polypeptides with two alternating amino acids, as expected from a triplet code. At least 20 codons are needed one for each amino acid There are only 42, or 16, different doublet nucleotide codons. whereas there are 43, or 64. different triplet codons. e- or double-nucleotide insertions or deletions in the rII gene resulted in a mutant phenotype, whereas three-nucleotide insertions or deletions resulted in a wild-type phenotype. Frameshift mutations can be reverted (.e.. the correct reading frame can be restored if another mutation in a different location within the same gene restores the reading frame. If the genetic code was structured with each codon consisting of either two or four nucleotides, insertion or deletion of a nucleotide would not cause the kind of frameshift mutation that Crick and colleagues had observed Submit My Answers Give Up Provide Feedback Continue e 40 58 PM l 3/28/2017

Explanation / Answer

the three correct statements are as follows:

1. in vitro translation of RNA composed of a dinucleotide repeat produced polypeptides with three alternating amino acids as expected from a triplet code.

2. at least 20 codons are needed one for each amino acid. there are only 42 or 16 different doublet codons whereas there are 43 or 64 different triplet codons.

3. if genetic code was structured with each codon consisting of either two or four nucleotides, insertion or deletion of a nucleotide would not cause the kind of frameshift mutation that Crick and colleagues had observed.