Corynebacterium diphtheria is the causal agent of the disease diphtheria. C. dip
ID: 225948 • Letter: C
Question
Corynebacterium diphtheria is the causal agent of the disease diphtheria. C. diphtheria produces a toxin that can cause cell damage. The diphtheria toxin is only produced under low extra-cellular concentration of iron (commonly found in host cells). The tax genes are under negative control wherein a regulatory protein, (DtxR) binds to the operator region when iron is present. Use figure 10.1 in your book, to determine which schematic in 10.1 best mirrors DtxR regulation below. Based on your conclusion, DtxR is acting as what? Iron would be a what? In which scenario (C or D) are the tox genes being transcribed? In the host with negligible iron (Fe): Not in the host, with iron plentiful:Explanation / Answer
4. DtxR is acting as to mediate the iron-dependent repression at Tox promoter.
5. Iron acts as a toxin ,
6. Figure D .