Pilot trial results are often used to estimate sample size needs for a full tria
ID: 242385 • Letter: P
Question
Pilot trial results are often used to estimate sample size needs for a full trial. Which statement about this issue is true?
The upper limit of the 95% CI around the pilot effect size should be used to estimate sample size needs.
Using the lower limit of the 68% CI around the pilot effect size to estimate sample size needs is considered acceptable by some experts.
Using the upper limit of the 68% CI around the pilot effect size to estimate sample size needs is considered acceptable by some experts.
The point estimate of the effect size from the pilot trial should be used to estimate sample size needs for the full trial.
A.The upper limit of the 95% CI around the pilot effect size should be used to estimate sample size needs.
B.Using the lower limit of the 68% CI around the pilot effect size to estimate sample size needs is considered acceptable by some experts.
C.Using the upper limit of the 68% CI around the pilot effect size to estimate sample size needs is considered acceptable by some experts.
D.The point estimate of the effect size from the pilot trial should be used to estimate sample size needs for the full trial.
Explanation / Answer
D.The point estimates of the effect size from the pliot trial should be used to estimate sample size needs for the full trial