Against gram-positive bacteria! Critical Thinking 1. What effect would the prese
ID: 252521 • Letter: A
Question
Against gram-positive bacteria! Critical Thinking 1. What effect would the presence of tetnacycline in the body have on penicillin therapy? bacteria In order to kut 'r, so pen ‘cu.n would be useless 2. The following results were obtained from a disk-diffusion test against a bacterium Antibiotic Zone of Inhibition (mm) 12 12 Which drug should be used to treat an infection caused by this bacterium Briefly explain. The broth dilation test can be used to determine the effectiveness of an antibiotic. In this test, serial diluti of the antbiotic were set up in the well of a microtiter plate. Equal amounts of broth culture of Staphylo cus acreas were added to each well. After incubation, the wells were examined for bacterial growth, wells? no growth were subcultured in nutrient broth without the antibiotic. Results were recorded as (+) for gro and (-) for no growth. 3. Growth Growth in Subculture Antibiotic Dilution 1:10 through 1:70 1:80 1:90 1:100 1:200 through 1:500 1:10 through 1:150 1:160 1:170 1:180Explanation / Answer
Tetracyclin and Penicillin are the antibiotics, antibiotic is the compound which eliminate the growth of bacteria, the antibiotic is used to treat the bacterial infection. Antibiotic are classified into two 1) bacteriostatic antibiotic and bactericidal antibiotic. The bactericidal antibiotic are potent in nature, it eliminate the growth of bacteria completely. The bacteriostatic antibiotics only stops the growth of bacteria that is it arrest the growth of bacteria in stationary phase
Tetracyclin is the bacteriostatic agent, it acts by inhibiting the 50S ribosomal subunit and inhibiting the binding of tRNA to the A site on the 30S ribosomal subunit and hence the protein will not be synthesized and replication will be halted and therefore the bacteria will be remain in the dormant and ultimately weakens and will facilitate to be destroy by the immune cells.
Penicillin is a bacteriocidal antibiotic, it acts by inhibiting the cross lining of nascent peptidoglycan through binding to penicillin binding protein. The cross linking occurs only when the nascent peptidlycan synthesized. If there is no protein to interact with penicillin therefore penicillin will not be effective.
The generally accepted explanation is that bactericides such as the penicillins, which inhibit bacterial cell wall synthesis, require cells to be actively growing and dividing to be maximally effective, a situation that will not occur in the presence of bacteriostatic antibacterials, such as the tetracyclines.
the drug is used to treat for the infection with this bacterium because it shows the larger zone of inhibition for the growth of this bacteria, that is more the zone of inhibition more susceptible is that bacteria for that drug hence the drug D will be effective to treat the infection caused by this bacterium