Case Stud The presenting symptom of a 40-year-old woman with rheumatoid arthriti
ID: 255005 • Letter: C
Question
Case Stud The presenting symptom of a 40-year-old woman with rheumatoid arthritis (RA) is a second deep vein thrombosis (DVT. No family history of thrombosis exists. PT: 12.7 sec aPTT: 50.2 sec PLT: 172 x 10/L 1. Interpret the coagulation screening tests. The results of additional studies were as follows Mixture of patient plasma and normal plasma (1:1): 49.8 sec Patient plasma with high-phospholipid reagent: 29.1 sec 2. Based on all the data provided, what condition is most likely? . What information was most useful in diagnosing the patient? se St A 30-year-old woman has experienced a third thrombotic episode after starting to take oral contraceptives. She has family members with a similar history PT: 12.0 sec aPTT: 26.8 sec PLT: 285 × 109/L 1. Interpret the coagulation screening tests. 2. What additional tests should be performed? Evaluate the results of the following additional studies: aPTT-based activated protein C (APC) resistance test: ratio of 1:6 (normal ratio 21:8) Factor V Leiden mutation molecular assay: positive (heterozygous) 3. Based on all the data provided, what condition is most likely? 4. What information is most diagnostic?Explanation / Answer
Case study 1:
1. The PT test is usually done to test the prothrombin time. The person has value of PT in normal range that usually seen during the medication like warfarin. This value suggests that time taken for the blood clot is in the range. The value of aPTT is little high from the normal range as the normal range is between 30 to 40 sec. The value of PTR is also under the normal range.
2. All the given data suggests that the person with the DVT is under the medication of blood thinning. This DVT is due to the RA as there is less movement of legs.
3. he most useful information was the values of tests as these values helps to tell the present condition of the patient.