Point mutations can cause (select all that apply): Silent mutations Missense mut
ID: 259868 • Letter: P
Question
Point mutations can cause (select all that apply):
Silent mutations
Missense mutations
Transversion mutations
Nonsense mutations
Frameshift mutations
2.
Insertions and deletions of three base pairs:
usually result in the expression of a truncated protein.
cause frameshifts that will change the reading frame and therefore the sequence of the protein.
do not disrupt the reading frame so the proteins ends up completely normal.
do not disrupt the reading frame so the protein will have an almost normal sequence.
3. Which of the following are true of chemotherapeutic agents? Select all that apply.
The adverse side-effects of chemotherapeutics are strongest in cell types that dividing rapidly (hair, blood and GI tract).
They create broken chromosomes or stalled replication forks.
These agents are toxic to cancer cells because they are part of a tumor.
The cytotoxic effect of these DNA damaging agents requires the cell to be actively dividing.
4.
Which statement below best describes an oncogene?
Gene that encodes for a protein that drives cell division forward.
Gene that encodes for a protein that blocks the cell cycle
5.
Which of the following is a correct pairing of a base to the product of its deamination?
Thymidine to uracil
Adenine to xanthine
5-methylcytosine to thymine
Cytosine to thymine
6.
Which of the following correctly describes the mechanism of a deamination reaction?
The 3' OH group attacks the nitrogen of a base.
An OH group from water attacks the base removing the amine group.
7.
The Ames test requires a specific strain of Salmonella that (select all that apply):
requires a lack of histidine in the media to survive.
may be able to survive without histidine if they get the proper reversion mutation.
is resistant to mutations.
is a histidine auxotroph.
Explanation / Answer
Point mutations can cause (select all that apply):
The answers are
Silent mutations
Missense mutations
Transversion mutations
Nonsense mutations
Explanation: During point mutation one nitrobase turns in another, due to this some time it may not be expressed i.e. silent, sometimes those may code for another amino acid i.e. missence or some times the purine turns in to pyrimidine or vice versa those are called as transversions and some times those may code for stop codon i.e. non sense mutations.
Frameshift mutations may occur due to addition or deletion of minimum of one nitrogen base. So, this is not the answer.
Insertions and deletions of three base pairs:
The answer is
usually result in the expression of a truncated protein.
Explanation:
cause frameshifts that will change the reading frame and therefore the sequence of the protein - as the codon composed with three nucleotides, the removal or addition of three nucleotides won't distrub the reading frame but it effects the protein sequence either by removing or addition of one amino acid.
do not disrupt the reading frame so the proteins ends up completely normal.
This either will delete or add the amino acid, so, the protein not endsup completely, so it won't be normal.
do not disrupt the reading frame so the protein will have an almost normal sequence.
This either will delete or add the amino acid, so, the protein not endsup completely, so it won't be normal.
According to chegg guidelines we have to answer one question at a time.So, post the rest as seperate questions then I can help you.