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Answer ALL questions please. ALL QUESTIONS 5) For each mutation listed below, ex

ID: 260446 • Letter: A

Question

Answer ALL questions please. ALL QUESTIONS

5) For each mutation listed below, explain the normal function of the gene product, state what will happen to the cell due to the mutation, and explain why this would happen CDK2 is permanently active, even when cyclin D (CDK2's activator) is absent from the cell. CDK1 is unable to bind to cyclin B (CDK1's activator). .A mutation prevents the nuclear envelope from breaking down. a) what areth iferencnrut of mitos d meé at as fferen i he to processes that creates these different end-products (specificalfnce what happens to the chromosomes)?

Explanation / Answer

5.

a. CDK2-E can't phosphorylate the RB protein and activate RB protein and which is activated by CDK4-D complex and inhibit several gene which is necessary for cell progression into S phase.

b. CDK1 binds with cyclin B us required for cell to enter into M phase.

c. If nuclear envelope is not broken then karyokinesis can't occur and cell will not divide.

6. Mitosis is cell divison taking place in all thesomatic cells and meiosis only takes place in germ cells to produce gametes. In mitosis two diploid daughter cells are produced and in meiosis four haploid daughter cells are produced.