Place the following statements/steps in the CORRECT order in accordance with Cel
ID: 262823 • Letter: P
Question
Place the following statements/steps in the CORRECT order in accordance with Cell mediated immunity. Give me an answer with in order like number 1-7
'APC breaks the antigen into smaller fragments/pieces.'
'Effector Helper T cells release cytokines signaling activated Cytotoxic T cells to undergo clonal expansion into Effector and Memory Cytotoxic T cells'
'The antigen fragments join and combine with MHC proteins = Ag-MHC complex.'
'Effector Cytotoxic T cells and Effector Helper T cells undergo apoptosis when the threat has diminished '
'An antigen-presenting cell (APC) such as a macrophage engulfs an antigen. '
'Helper and Cytotoxic T cells recognize and bind Ag-MHC; Cytotoxic T cells activated and Helper T cells undergo clonal expansion into Effector and Memory Helper T cells'
'Effector Cytotoxic T cells circulate and signal infected cells to undergo apoptosis'
Explanation / Answer
1) An antigen presenting cells (APC) such as a macrophage engulf an antigen.
2) APC breaks the antigen into smaller fragments or pieces.
3) The antigen fragments join and combine with MHC proteins=Ag-MHC complex.
4) Helper and Cytotoxic T cells recognise and bind Ag-MHC; Cytotoxic T cells activated and helper T cells undergo clonal expansion into effector and memory helper T cells.
5) Effector helper T cells release Cytokines signalling activated Cytotoxic T cells to undergo clonal expansion into effector and memory cytoCytot T cells.
6) Effector Cytotoxic T cells circulate and signal infected cells to undergo apoptosis.
7) Effector Cytotoxic T cells and effector helper T cells undergo apoptosis when the threat has diminished.