Please answer the following questions: 1. In situ hybridization is to immunohist
ID: 266369 • Letter: P
Question
Please answer the following questions:
1. In situ hybridization is to immunohistochemistry as:
a. Northern blot is to Southern blot
b. Southern blot is to Northern blot
c. Northern blot is to western blot
d. western blot is to northern blot
e. southern blot is to western blot
2. In the developing Drosophila embryo, the Hox genes are expressed:
a. in temporally restricted domains
b. in spatially restricted domains
c. uniformly throughout the embryo
d. only in the homeotic mutants
e. None of the above are correct
3. A patient has a genetic disease and pays for exome sequencing in an attempt to identify the genetic polymorphism leading to the disease. all isolated exome sequences are identical when compared to a reference genome. what type of mutations may explain why no polymorphisms are identified?
a. the mutation is an enhancer
b. the mutation is in a repressor
c. the mutation is a deletion encompassing an exon
d. A and B only
e. A and C only
Explanation / Answer
1. Option C is correct.
Insitu and Northern blotting= RNA
Immunohistochemistry and Western blotting= Protein
2. Option B is correct.
In the developing Drosophila embryo, Hox genes are expressed in a spatially restricted domain.
3. Option D is correct.
The mutation is in the cis elements. i.e. enhancer or repressor