Blood flow at the site of drug administration is an important aspect of drug abs

Question

Blood flow at the site of drug administration is an important aspect of drug absorption. Which of the following statements is true? a. Infants have lower lean body mass and lower peripheral perfusion, leading to b. Elderly have less muscle mass and therefore more water in their body on a c. Pregnant women have decreased blood flow and therefore are a challenging d. Adverse therapeutic effects are more common in infants than adults or the impaired drug absorption percent mass basis. patient group for injection-based drugs. elderly because infant livers are still developing over the course of their first year of life.

Explanation / Answer

Option a is correct because drug absorption is influenced by many factors such as gastric emptying ,intestinal motility and lower lean body massage.These process are decreased in infants.So these factors impair drug absorption in infants.

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